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Abstract #2412

The value of whole volume radiomics machine learning model based on multi-parameter MRI in predicting triple negative breast cancer

Tingting Xu1, Xueli Zhang1, Ting Hua1, Guangyu Tang1, lin Zhang1, and Xiance Zhao2
1Radiology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China, 2Philips Healthcare, Shanghai, China

Synopsis

Keywords: Radiomics, Machine Learning/Artificial Intelligence, Triple-negative breast cancer. DCE-MRI. ADC maps43 TNBCs and 84 Non-TNBCs were allocated in this retrospective study.The lesions were manually segmented with ITK-SNAP software then whole volume radiomics features were extracted with Radcloud radiomics platform based on DCE-MRI and ADC maps, respectively. Three prediction models were constructed by using support vector machine (SVM) classifier, including Model A (based on the selected features of ADC maps), Model B (based on the selected features of DCE-MRI), and Model C (based on the selected features of both combined). The radiomics features model combining DCE-MRI and ADC maps can improve the diagnostic performance of predicting TNBC.

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Keywords