Abstract #2419

Exposure to Welding Fumes: Evaluating the metabolite-metal relationship

Gianna Nossa¹, Humberto Monsivais², Chang Guen Lee², Jae Hong Park², and Ulrike Dydak^2,3

¹Purdue University, West Lafayette, IN, United States, ²School of Health Science, Purdue University, West Lafayette, IN, United States, ³Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States

Synopsis

Keywords: Data Analysis, ToxicityChronic exposure to Mn and Fe, through inhalation of welding fumes, is known to cause neurotoxicity. In this MRS study, we aim to determine if toenail Mn and Fe levels can be predictive of neurotoxicity identified through changes in GABA, GSH, and/or Glu concentrations. Significant GABA and GSH correlations with Fe indicate that toenail Fe concentrations can reflect decreased GABA and GSH levels in the welders’ brain. This emphasizes that Fe should not be ignored and might contribute to oxidative stress in Mn neurotoxicity.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.