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Abstract #2440

Free-Breathing, Gadoxetic Acid Enhanced, 3D T1w Phase Sensitive Inversion Recovery Hepatobiliary MRI Optimized for 3.0 Tesla

Yavuz Muslu1,2, Ty A. Cashen3, Sagar Mandava4, Diego Hernando2,5, and Scott B. Reeder1,2,5,6,7
1Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 2Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, 3Global MR Applications and Workflow, GE Healthcare, Waukesha, WI, United States, 4Global MR Applications and Workflow, GE Healthcare, Atlanta, GA, United States, 5Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 6Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States, 7Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Liver, Image ReconstructionGadoxetic acid (GA)-enhanced hepatobiliary phase (HBP) T1-weighted (T1w) MRI is well established for the detection of focal liver lesions. Previously, we proposed a novel imaging method to improve T1 contrast in GA-enhanced HBP T1w images for the purpose of improved detection and characterization of liver lesions. The proposed method provides volumetric, high-resolution phase-sensitive inversion recovery (PSIR) T1w images of the liver from a free-breathing image acquisition. This study focuses on the impact of flip angle and spoiling on image quality. Our findings indicate 6-8 degrees flip angle in combination with gradient spoiling provides optimal image quality and T1 contrast.

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