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Abstract #2465

Scan-Rescan Repeatability of 10-Minutes Long MAPSS Sequence for Simultaneous MR T2 and T1ρ Mapping of Cartilage and Meniscus at 7 Tesla

Stefan Zbyn1,2,3, Richard Lartey1,2, Jeehun Kim1,2, Carl S. Winalski1,2,3, and Xiaojuan Li1,2,3
1Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, 2Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States, 3Department of Diagnostic Radiology, Imaging Institute, Cleveland Clinic, Cleveland, OH, United States

Synopsis

Keywords: Cartilage, Relaxometry, MeniscusThe aim of this study was to evaluate the in vivo scan-rescan repeatability of T2 and T1ρ quantification in knee cartilage and meniscus of patients with knee pain at 7 Tesla. Four subjects were scanned-rescanned on the same day using the 10-minutes-long MAPSS sequence for simultaneous T2 and T1ρ mapping. Coefficients of variation and Bland-Altman plots showed excellent scan-rescan repeatability of in vivo T2 and T1ρ quantification in cartilage and meniscus at 7 Tesla. Our results indicate that fast T2 and T1ρ mapping with four echo and four spin-lock times remains sensitive to cartilage degeneration.

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Keywords