Abstract #2465

Scan-Rescan Repeatability of 10-Minutes Long MAPSS Sequence for Simultaneous MR T2 and T1ρ Mapping of Cartilage and Meniscus at 7 Tesla

Stefan Zbyn^1,2,3, Richard Lartey^1,2, Jeehun Kim^1,2, Carl S. Winalski^1,2,3, and Xiaojuan Li^1,2,3

¹Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, ²Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States, ³Department of Diagnostic Radiology, Imaging Institute, Cleveland Clinic, Cleveland, OH, United States

Synopsis

Keywords: Cartilage, Relaxometry, MeniscusThe aim of this study was to evaluate the in vivo scan-rescan repeatability of T2 and T1ρ quantification in knee cartilage and meniscus of patients with knee pain at 7 Tesla. Four subjects were scanned-rescanned on the same day using the 10-minutes-long MAPSS sequence for simultaneous T2 and T1ρ mapping. Coefficients of variation and Bland-Altman plots showed excellent scan-rescan repeatability of in vivo T2 and T1ρ quantification in cartilage and meniscus at 7 Tesla. Our results indicate that fast T2 and T1ρ mapping with four echo and four spin-lock times remains sensitive to cartilage degeneration.

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