Abstract #2466

Bi-exponential 3D UTE-T1rho relaxation mapping of ex-vivo human knee patellar tendon at 3T

Bhavsimran Malhi¹, Dina Moazamian¹, Michael Carl², Jiyo Athertya¹, Saeed Jerban¹, Hyungseok Jang¹, Yajun Ma¹, Eric Chang^1,3, and Jiang Du^1,4,5

¹Department of Radiology, University of California, San Diego, USA, San Diego, CA, United States, ²GE Healthcare, San Diego, USA, San Diego, CA, United States, ³Veterans Affairs San Diego Helath Care system, San Diego, USA, San Diego, CA, United States, ⁴Veterans Affairs San Diego Health Care System, San Diego, CA, USA, San Diego, CA, United States, ⁵Department of Bioengineering, University of California, San Diego, USA, San Diego, CA, United States

Synopsis

Keywords: Tendon/Ligament, Tendon/Ligament, UTE, MRI

UTE sequences have been previously used to image short T2 tissues. T1ρ has shown promising results in assessing macromolecules and has been proposed as a potential biomarker for tissue degeneration. In this study, we aimed to demonstrate bi-exponential relaxation of the patellar tendon at 3T, using the 3D ultrashort echo time T1ρ (UTE-T1ρ) sequence. Five ex-vivo knee joints were scanned, and we were able to demonstrate better fitting with a bi-component model and better discern the long and short relaxation components of the tissue, along with their respective fractions

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