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Abstract #2493

Optimization of 2D-APT imaging of brain tumor based on saturated RF pulse parameters

na liu1, ailian liu2, peng sun1, qingwei song1, and yanwei miao3
1The First Affiliated Hospital of Dalian Medical University, DaLian, China, 2The First Affiliated Hospital of Dalian Medical University, Dalian, China, 3The First Affiliated Hospital of Dalian Medical University, dalian, China

Synopsis

Keywords: Tumors, Molecular Imaging2D APTw imaging is a single-slice imaging method focusing on the selected plane, with low spatial coverage and a much shorter scan time than its 3D counterpart, which makes it an optional scan sequence for patients who cannot tolerate long scan times. However, there is still a lack of an optimal setting for 2D APTw imaging in clinics for human brain tumors. Therefore, this study aims to explore the different combinations of pulse power and duration of saturation RF pulse in 2D APTw imaging on brain tumors and to find an optimal setting suitable for clinical use.

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