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Abstract #2527

Functional plasticity development of visual-motor cortex in neonatal brain is modulated by postnatal experience

Yifan Shuai1, Ruolin Li1, Yihan Wu1, Zhiyong Zhao1, and Dan Wu1
1Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China

Synopsis

Keywords: Neonatal, Normal development, functional plasticityThe present study aimed to investigate how the brain entropy (BEN) changes with age during early development and whether it exists differences between term- and preterm-born neonates. The results found that the BEN in visual-motor cortex was positively correlated with PMA but had no significant correlation with GA, which showed an increase in preterm- than term-born neonates with matched PMA. Moreover, both age and preterm have a significant effect on the functional connectivity between visual-motor cortex and other regions. These findings suggest the functional plasticity development of visual-motor cortex is modulated by early postnatal experience in human neonates.

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Keywords