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Abstract #2532

Harmonization of Multi-Site rs-fMRI data using CovBat

Katherine Breedlove1,2, Hector Arciniega1,2, Sylvain Bouix3, Martha Shenton1,2, and Alexander Lin1,2
1Brigham and Women's Hospital, Boston, MA, United States, 2Harvard Medical School, Boston, MA, United States, 3University of Quebec, Montreal, QC, Canada

Synopsis

Keywords: Software Tools, fMRI (resting state)Multisite studies are an important feature of modern neuroimaging research as they allow the study of larger and more diverse populations, which is essential to obtain clinically relevant insight and sensitivity to subtle effects. However, due to the variability among scanner platforms, even when utilizing the same acquisition protocols, harmonization is needed to remove site-to-site variability in order to improve signal-to-noise ratio and improve statistical power. By implementing CovBat as a BIDS application, we have created a turnkey application that quickly minimizes confounding signals in multisite fMRI studies.

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Keywords