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Abstract #2548

Physiological contributions of ECG-derived respiration to BOLD fluctuations during resting-state and respiratory modulations

Inês Esteves1, Ana R. Fouto1, Amparo Ruiz-Tagle1, Gina Caetano1, and Patrícia Figueiredo1
1ISR-Lisboa and Department of Bioengineering, Instituto Superior Técnico – Universidade de Lisboa, Lisbon, Portugal

Synopsis

Keywords: fMRI, Multimodal, ECG, respirationPhysiological signal acquisition during fMRI may be used for multiple purposes, though it usually requires additional setup which may increase complexity and cause subject discomfort. Since ECG is modulated by respiration, an ECG-derived respiration (EDR) may be obtained without needing extra equipment for EEG-fMRI studies, which inherently use the ECG. In this work, EDR signals were computed for resting-state and two respiratory challenges modulating respiration patterns, to validate their use in the MR environment. Their performance for estimating physiological regressors of BOLD-fMRI signals was similar to the one obtained by using concurrently acquired respiratory signals.

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Keywords