Abstract #2550

Multi-shot Diffusion-weighted Imaging of the Breasts in the Supine versus Prone Position

Catherine J. Moran¹, Matthew J. Middione¹, Valentina Mazzoli¹, Jessica A. McKay-Nault¹, Arnaud Guidon², Uzma Waheed¹, Eric L. Rosen¹, Steven P. Poplack¹, Jarrett Rosenberg¹, Daniel B. Ennis¹, Brian A. Hargreaves¹, and Bruce L. Dnaiel¹

¹Radiology, Stanford University, Stanford, CA, United States, ²General Electric Healthcare, Boston, MA, United States

Synopsis

Keywords: Breast, Diffusion/other diffusion imaging techniques

Diffusion-Weighted Imaging (DWI) allows for the detection of breast cancer without a contrast injection, while supine positioning may improve the comfort and efficiency of a breast MRI screening exam. This work investigates multi-shot DWI of the breasts in the supine versus prone positions, in both asymptomatic volunteers and patients with breast lesions. Supine multi-shot DWI outperformed prone multi-shot DWI based on an image quality observer study, receiving significantly higher ratings for sharpness, aliasing, and overall image quality. Lesion Apparent Diffusion Coefficients (ADCs) were highly correlated between the two positions, while fibroglandular tissue ADCs were significantly higher in the supine position.

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