Abstract #2567

Longitudinal assessment of variability in a multicenter MRI QC program using the CaliberMRI breast phantom: protocol adherence and ADC values

Lisa J. Wilmes¹, Jessica E. Gibbs¹, Nu N. Le¹, Todor Karaulanov², David C. Newitt¹, Kathryn E. Keenan³, Alina Tudorica⁴, Gwen Bowden⁵, Yucheng Liu⁶, Lauren Fang⁷, Patrick J. Bolan⁸, Dariya Malyarenko⁹, Thomas L. Chenevert⁹, David Van Wie¹⁰, Chelsea Pyle⁴, Bethany Niell⁵, Richard Ha⁶, Rebecca Rakow-Penner⁷, Haydee Ojeda-Fournier⁷, An Church⁸, Bonnie N. Joe¹, and Nola M. Hylton¹

¹University of California San Francisco, San Francisco, CA, United States, ²CaliberMRI, Boulder, CO, United States, ³National Institute of Standards and Technology, Boulder, CO, United States, ⁴Oregon Health & Science University, Portland, OR, United States, ⁵Moffitt Cancer Center, Tampa, FL, United States, ⁶Columbia University Medical Center, New York, NY, United States, ⁷University of California San Diego, San Diego, CA, United States, ⁸University of Minnesota Medical School, Minneapolis, MN, United States, ⁹University of Michigan Health System, Ann Arbor, MI, United States, ¹⁰Boulder Labs, Boulder, CO, United States

Synopsis

Keywords: Breast, Diffusion/other diffusion imaging techniquesCaliberMRI’s multiparametric quantitative breast MRI phantom was scanned with a standard protocol, including DWI, at seven clinical sites as part of a quality control program. Protocol adherence was assessed. ADC values for fibroglandular and malignant breast tissue DWI mimics were calculated and corrected for temperature using the qCal software, and summary reports were generated. Inter- and intra-site variations in ADC derived from DWI phantom scans acquired longitudinally over the last 16 months provided information that can be used to troubleshoot imaging acquisition issues with sites and vendors as part of a phantom-based QC program.

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