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Abstract #2574

Optimal PLD selection for White Matter perfusion measurements at 7T.

Emiel C.A. Roefs1, Lydiane Hirschler1, Natalia Petridou2, and Matthias J.P. van Osch1
1Radiology, C.J. Gorter MRI Center, Leiden Univeristy Medical Center, Leiden, Netherlands, 2Radiology, Center for Image Sciences, Univeristy Medical Center Utrecht, Utrecht, Netherlands

Synopsis

Keywords: Arterial spin labelling, High-Field MRIWhite matter (WM) perfusion measurements are challenging because of the generally lower perfusion in combination with a longer bolus arrival time (BAT). We investigated the use of long-PLD perfusion measurements at high-field (7T) to compensate for longer BAT in WM. We showed that 3D background suppressed FAIR at 7T with a PLD of 2300ms provides robust perfusion measurement in almost 80% of deep WM within 4min of scan time.

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