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Abstract #2579

Investigating border zone hemodynamics with time-encoded super-selective pCASL in internal carotid and basilar artery perfusion territories

Lena Vaclavu1 and Matthias JP van Osch1
1C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

Synopsis

Keywords: Arterial spin labelling, Perfusion, super-selective, time-encoded, borderzonesThe borders between cerebral perfusion territories are regions of the brain that are susceptible to infarction. In this study, time-encoded super-selective pCASL was implemented to study the hemodynamic properties of the border zones between the left internal carotid artery and basilar artery perfusion territories. Perfusion territories were well-defined with little-to-no detectable overlap. The longest arrival times were found at the border zones, compared to 'inland' of the perfusion region. Combining time-encoded with super-selective pCASL enables the simultaneous investigation of border zones and their arrival times.

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