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Abstract #2590

A novel registration strategy to transform skeletal muscle architecture during passive shortening

Melissa T. Hooijmans1,2,3, Carly Lockard2, Crystal Coolbaugh1, Mark George1, Xingyu Zhou1,2,4, and Bruce Damon1,2,4
1Institute of Imaging Sciences, Vanderbilt University, Nashville, TN, United States, 2Carle Health, Stephens Family Clinical Research Institute, Urbana, IL, United States, 3Radiology and Nuclear Medicine, University of Amsterdam, Amsterdam Movement Sciences, Amsterdam UMC, Amsterdam, Netherlands, 4Biomedical Engineering, Vanderbilt University, Nashville, TN, United States

Synopsis

Keywords: Muscle, Diffusion Tensor Imaging, Muscle architectureIn this study we explored if displacement fields, derived from registration of high-resolution anatomical images in different foot positions, could be used to transform muscle fiber architecture from plantar-flexed to dorsi-flexed foot position (passive shortening). Our data revealed that muscle fiber architecture from one foot position can be transformed in the other foot position and that the original and transformed fibers demonstrate similar architectural characteristics, i.e. fiber lengths, pennation angle, curvature, and physiological cross-sectional area.

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