Keywords: Muscle, Fat, Quantitative imaging, Lumbar disc herniationPrevious study found that low back pain (LBP) and Modic changes were closely associated with fatty infiltration and cross-sectional area (CSA) of the paraspinal muscles. However, conflicting evidences were reported. This study investigated the association between intervertebral discs degeneration and lumbar paraspinal muscles CSA and fat infiltration, and explored the relationship between Modic change and intervertebral discs degeneration. Our results found that lumbar disc’s Pfirrmann grading was weakly correlated with CSA of multifidus, fat fraction of multifidus and erector spinae, and the incidence rate of Modic changes increased in higher Pfirrmann grading.
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