Abstract #2602

Assessment of Rabbit Intervertebral Disc Degeneration Using Quantitative MR Imaging

Jiyo S Athertya¹, James Lo^1,2, Alicia Ji¹, Charles Ding¹, Arya Suprana^1,2, Kiersten Red³, Yujia Ge³, Madeline Brown ³, Jiang Du^1,2,4, Eric Y Chang^1,4, Koichi Masuda ³, and Yajun Ma¹

¹Radiology, UC San Diego, San Diego, CA, United States, ²Bioengineering, UC San Diego, San Diego, CA, United States, ³Orthopedic Surgery, UC San Diego, San Diego, CA, United States, ⁴Radiology, Veterans Affairs San Diego Healthcare System, San Diego, CA, United States

Synopsis

Keywords: MSK, Joints, Intervertebral discIntervertebral disc degeneration is a leading cause of disability. In this study, quantitative T2 and ultrashort echo time magnetization transfer ratio (UTE-MTR) measurement techniques are utilized to assess biochemical component changes for better understanding of the mechanism of disc degeneration using a rabbit spinal intervertebral disc degeneration model. Both T2 and UTE-MTR values of nucleus pulposus (NP) are significantly different between normal and degenerated discs, indicating water and/or proteoglycan content changes.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.