Abstract #2606

Association of Lumbar Trabecular Bone Ultrashort Echo Time Magnetization Transfer Ratio (UTE-MTR) with Intervertebral Disc Degeneration

Jian-Bang Zhang¹, Jin Liu¹, Jia-Xin Feng¹, Jianwei Liao¹, Wei Li¹, Xiao-Jun Chen¹, Long Qian², Ya-Jun Ma³, and Shao-Lin Li¹

¹Department of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China, ²GE Healthcare, Beijing, China, ³Department of Radiology, University of California San Diego, San Diego, CA, United States

Synopsis

Keywords: Bone, SkeletalUltrashort echo time magnetization transfer (UTE-MT) technique can non-invasively quantify the macromolecular component changes. It has great potential to assess intervertebral disc degeneration (IVDD). In this study, we utilized the UTE-MT sequence to investigate the relationship between UTE-MT ratio (UTE-MTR) measurements of lumbar trabecular bone and IVDD. We found that the lumbar trabecular bone UTE-MTR negatively correlated with the IVDD grading. It demonstrates that the UTE-MTR of lumbar trabecular bone may serve as a useful biomarker to assess IVDD.

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