Abstract #2607

Lumbar spine disc degeneration assessed by in vivo 3T multifrequency MR elastography

Rolf Reiter^1,2, David Kaufmann³, Mehrgan Shahryari¹, Janosch Simon Jahn¹, Rebecca Strehle¹, Christian Bayerl¹, Bernd Hamm¹, Jürgen Braun⁴, Ingolf Sack¹, and Patrick Asbach¹

¹Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ²BIH Biomedical Innovation Academy, BIH Charité Digital Clinician Scientist Program, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany, ³Radiology, Universitätsklinikum Augsburg, Augsburg, Germany, ⁴Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany

Synopsis

Keywords: Elastography, MSK

Despite the success in detecting intervertebral disc degeneration with high-resolution T2 sequences, conventional MRI is limited by large inter-reader variability as well as lacking stratification of clinical trials and their assessment of treatment responses. Several studies have shown the technical feasibility of MR elastography for the study of the intervertebral disc, but its clinical relevance remains unclear. This study shows an excellent diagnostic performance of high-resolution multifrequency MR elastography in the evaluation of lumbar spine intervertebral disc degeneration.

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