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Abstract #2611

Effects of HIV-associated chronic inflammation on intracranial vessels using semi-automatic segmentation of MRA cerebrovascular features

Nhat Hoang1, Henry Wang2, Sahin Bogachan3, Muhammad Waqas Khan4, Abrar Faiyaz5, Meera Singh3, Jinjiang Pang6, Shumin Wang6, Li Chen7, Chun Yuan7, Jianhui Zhong1, Hongmei Yang8, Md Nasir Uddin3, and Giovanni Schifitto3
1Physics, University of Rochester, Rochester, NY, United States, 2Radiology, University of Rochester, Rochester, NY, United States, 3Neurology, University of Rochester, Rochester, NY, United States, 4Neurology-Stroke Division, University of Rochester, Rochester, NY, United States, 5Department of Electrical and Computer Engineering, University of Rochester, Rochester, NY, United States, 6Cardiology Research, University of Rochester, Rochester, NY, United States, 7Department of Electrical and Computer Engineering, University of Washington, Seattle, WA, United States, 8Biostatistics, University of Rochester, Rochester, NY, United States

Synopsis

Keywords: Neuroinflammation, Vessels, MRA, CSVD, HIVHIV infected individuals (HIV+) are subjected to high risks of neurological complications, including cerebrovascular disease. Quantification of vascular features may provide a tool to investigate pathomechanisms and monitor cerebrovascular disease progression. In this study we used intracranial artery feature extraction (iCafe) to compare HIV+ with age matched controls.

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Keywords