Abstract #2617

Diffusion tensor imaging study of white matter differences between autoimmune encephalitis and viral encephalitis

Qingrui Li¹, Xiarong Gong², Qiu Bi², Yunzhu Wu³, and Kunhua Wu²

¹Kunming University of Science and Technology, Kunming, China, ²the Affiliated Hospital of Kunming University of Science and Technology, Kunming, China, ³MR Scientific Marketing, Siemens Healthineers, Shanghai, China

Synopsis

Keywords: Neuroinflammation, Diffusion Tensor Imaging, encephalitis

In this study, diffusion tensor imaging (DTI) analysis based on Tract-based spatial statistics (TBSS) was used to investigate the microstructural changes of white matter (WM) in viral encephalitis (VE) and autoimmune encephalitis (AE). The study found that WM injury degree in patients with VE and AE was different. The DTI parameters can separate AE, VE and healthy control group. The study results indicate that DTI could serve the function of early diagnosing and distinguishing AE from VE, and provide imaging evidence for the pathophysiological changes of WM in AE and VE patients.

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