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Abstract #2712

Using interpretable deep learning on task fMRI data to understand brain regions related to working memory - a repeatability study

Tianyun Zhao1, Philip Tubiolo1,2, Thomas Hagan1, John C. Williams1,2, Jared Van Snellenberg2,3,4, and Chuan Huang1,4
1Biomedical Engineering, Stony Brook University, Stony Brook, NY, United States, 2Psychiatry and Behavioral Health, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, United States, 3Psychology, Stony Brook Univeristy, Stony Brook, NY, United States, 4Radiology, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, United States

Synopsis

Keywords: Machine Learning/Artificial Intelligence, fMRI (task based)Deep learning, especially convolutional neural networks (CNN), has been shown to be able to identify the non-linear relation between functional magnetic resonance imaging (fMRI) and task performance. CNN can generate an interpretable result called saliency map highlighting regions that are important for task performance. It can uncover other neural processes that linear modeling cannot due to the high dimensionality nature of the fMRI. The CNN result can be presented as a saliency Previously, we developed a pipeline to produce the saliency map for working memory tasks. In this work, we further evaluated the repeatability of our pipeline.

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Keywords