Abstract #2723

Reliability and sensitivity of fMRI at 3T and 1.5 T: metrics toward fMRI guided individualized precise TMS treatment

Qiu Ge^1,2,3, MinLiang Yao⁴, Juan Yue^1,2,3,4, Xue Yang^1,2,3, YueJiao Ding^1,2,3, Yong Zhang⁵, and Yufeng Zang^1,2,3,4

¹Center for Cognition and Brain Disorders, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China, ²Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, HangZhou, China, ³Institute of Psychological Sciences, Hangzhou Normal University, HangZhou, China, ⁴Hangzhou Normal University Affiliated Deqing Hospital, HangZhou, China, ⁵Yong Zhang, GE Healthcare, Shanghai, China

Synopsis

Keywords: Data Acquisition, fMRIFDA cleared a TMS treatment protocol with fMRI-guided individualized targeting for major depressive disorder. This protocol was based on 3T scanner. However, 1.5 T MRI is more widely available in hospitals. We comprehensively tested the reliability and sensitivity of fMRI metrics related to TMS treatment on 1.5T and 3T scanners. In general, the sensitivity of 3T is larger than 1.5T. However, the reproducibility of peak FC location and the activation location, the reliability of RS-fMRI local metrics, are similar for 1.5T and 3T. In conclusion, 1.5 fMRI meets the needs for guiding individualized precise rTMS treatment.

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