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Abstract #2728

Diagnostic value of APT, DWI, and DCE-MRI in molecular classification and prognosis of breast cancer

Xiaoyan Liu1,2, Baojian Wang2, Litao Zhang1, Zhenbo Ma1, Yanlei Wang2, Yishi Wang3, Xiujuan Li1, and Yuanzhong Xie1
1Taian City Central Hospital, Taian, China, 2Shandong First Medical University, Taian, China, 3Philips Healthcare, Beijing, China

Synopsis

Keywords: Breast, CEST & MT, Tumor;Amide proton transfer imaging;According to the molecular classification of breast cancer, the clinical therapeutic strategy is formulated. Currently, the diagnostic value of amide proton transfer (APT) imaging in breast cancer is still unclear. This study aims to explore the diagnostic value of APT, DWI, and DCE-MRI in the molecular classification and prognosis of breast cancer. Our results showed that there were differences in TTP and BE values between luminal and non-luminal subtypes of breast cancer. The combination of APT, DWI, and DCE-MRI had the highest diagnostic efficiency. APT, DWI, and DCE-MRI parameters were correlated with different prognostic factors of breast cancer.

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Keywords