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Abstract #2729

Diagnostic performance of DCE-MRI for the axillary sentinel lymph nodes status in breast cancer patients

Fang Xiao1, Mingli Jin2, Peng wang1, Zhihua Pan2, Qi Zhao2, Ying Jiang2, Miaoqi Zhang3, and Yong Zhang3
1Department of Radiology,The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China, 2The Second Affiliated Hospital of Chengdu Medical College, Nuclear Corportation 416 Hosptital, chengdu, China, 3GE Healthcare, MR Research, Beijin, China

Synopsis

Keywords: Breast, Cancer, contrast-enhanced (DCE) MRI, sentinel lymph nodesSentinel lymph nodes(SLN) status is one of the most important indicators affecting breast cancer patient treatment and prognostic. Thus, a non-invasive diagnostic method capable of accurately predicting of the SLN status is of great value in selecting breast cancer patients who would benefit from therapy. In this study, we investigate the diagnostic performance of different SLN status [pN0, pN0 (i+), pN1mi, and pN1] using dynamic contrast-enhanced (DCE) MRI.We found that (1) Krans, Kep, and Ve are significantly different in different SLN status, (2) and the Ktrans is the best single parameter for the detection of SLN status.

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