Abstract #2730

Comparison of DWI score and Kinetic score as a Prognostic Marker in Breast Cancer Patients receiving Neoadjuvant Systemic Treatment.

Rie Ota¹, Masako Kataoka², Mami Iima², Maya Honda³, Aika Okazawa², Yosuke Yamada⁴, Yasuhide Takeuchi⁴, Masakazu Toi⁵, Takeshi Kubo¹, and Yuji Nakamoto²

¹Department of Radiology, Tenri Hospital, Nara, Japan, ²Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University graduate school of medicine, Kyoto, Japan, ³Department of Diagnostic Radiology, Kansai Electric Power Hospital, Osaka, Japan, ⁴Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan, ⁵Department of Breast Surgery, Kyoto University Hospital, Kyoto, Japan

Synopsis

Keywords: Breast, Cancer, disease-free survival This study aimed to investigate the association of DWI score of breast cancer derived from MRI obtained after neoadjuvant systemic treatment (NST) with disease-free survival (DFS). Kinetic score from standard DCE-MRI at the same timing was analyzed for comparison. Kaplan-Meier analysis showed that patients with DWI score of 2 showed significantly shorter DFS than those with DWI score 0 or 1. Patients with kinetic score of 2 or 3 showed significantly shorter DFS than those with kinetic score of 0 or 1. DWI score demonstrated excellent inter-reader agreement and is suitable for predicting prognosis of breast cancer patients after NST.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.