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Abstract #2736

Ultrashort Echo Time (UTE) MRI in the Detection and Classification of Microcalcification in Breast Cancer

Yazan Ayoub1, Sai Man Cheung1, Boddor Maglan1, Ehab Husain2, Yazan Masannat3, and Jiabao He1,4
1Aberdeen Biomedical Imaging Centre, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom, 2Department of Pathology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom, 3Breast Unit, Aberdeen Royal Infirmary, Aberdeen, United Kingdom, 4Newcastle Magnetic Resonance Centre, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, United Kingdom

Synopsis

Keywords: Breast, Cancer

Micro-calcification is a central feature of breast cancer, and clinically revealed on mammography. Mammography, a two dimensional imaging approach, is inadequate to provide refined classification. Conventional MRI cannot capture the rapid signal decay from micro-calcification, with Ultra Short Echo Time (UTE) developed to image short T2* species. UTE demands precise control of the hardware to minimise the time delay between radiofrequency transmission and image acquisition, while substantial effort is required to optimise image quality and contrast. We set out to examine the degree of calcification in breast tumour specimens freshly excised from patients using UTE, with comparison against histopathological findings.

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Keywords