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Abstract #2745

Multi-2D ASL-MRA and super-resolution convolutional neural network for improved intracranial peripheral arteries visualization

Yuriko Suzuki1, Ioannis Koktzoglou2,3, Peter Jezzard1, and Thomas Okell1
1Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 2Department of Radiology, NorthShore University HealthSystem, Evanston, IL, United States, 3Pritzker School of Medicine, University of Chicago, Chicago, IL, United States

Synopsis

Keywords: Arterial spin labelling, Blood vessels, MRAThe non-invasive nature of Arterial Spin Labeling (ASL) technique makes ASL-based intracranial dynamic MR angiography (MRA) a potential alternative to diagnostic X-ray digital subtraction angiography. In elderly and diseased patients with slower blood flow, however, the vessel visualization of distal peripheral arteries tends to be poor, as the repeatedly applied RF excitation pulses decrease ASL blood signal rapidly. In this study, we address such a limitation by using multiple 2D slice acquisition to reduce the saturation of arterial blood signal. Additionally, to avoid losing vessel conspicuity and sharpness with 2D slice acquisition, we apply a super-resolution convolutional neural network method.

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Keywords