Abstract #2756

A Mathematical Model for Velocity-Selective Arterial Spin Labeling

Thomas Liu^1,2,3,4, Eric Wong^1,2,3, Divya Bolar^1,2, Conan Chen^1,2,5, and Ryan Barnes^1,5

¹Center for fMRI, University of California San Diego, La Jolla, CA, United States, ²Department of Radiology, UCSD, La Jolla, CA, United States, ³Department of Psychiatry, UCSD, La Jolla, CA, United States, ⁴Department of Bioengineering, UCSD, La Jolla, CA, United States, ⁵Department of Electrical and Computer Engineering, UCSD, La Jolla, CA, United States

Synopsis

Keywords: Arterial spin labelling, Arterial spin labellingA mathematical model is presented that describes the arterial delivery function and cerebral blood volume components in velocity-selective arterial spin labeling. The model incorporates physiologically valid approximations of changes in acceleration and velocity along the vascular system. Applications of the model are shown using a set of example labeling and saturation profiles.

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