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Abstract #2772

Alteration in microcirculation with osteonecrosis of the femoral head: Study on Dynamic Contrast-enhanced MRI

Huan Da Wei1, Yuan Zhao Feng1, Dou Wei Qiang2, Wen Qing Qing2, Liu Shao Wei1, Lu Chao1, Zhang Chao1, Xia Tian Wei1, and Shen Ji Rong1
1Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Nanjing, China, 2MR Research China, GE Healthcare, Beijing, China

Synopsis

Keywords: Joints, DSC & DCE PerfusionOsteonecrosis of femoral head (ONFH) occurs due to a defect in the blood supply to the femoral head. In this study, Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) was applied to ONFH patients in different stages to explore the perfusion changes in the progression of the severity of ONFH. It was found that perfusion in the necrotic area was persistently reduced, while in the repair reaction areas, perfusion was progressively enhanced. DCE-MRI can sensitively detect the perfusion changes of ONFH and potentially could predict ONFH development.

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