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Abstract #2792

The value of MR diffusion tensor imaging in assessing white matter changes in short-term methamphetamine withdrawal

Yanyao Du1, Wenhan Yang1, Sihong Huang1, Fei Tang1, Wei Zhao1, Hu Guo2, Huiting Zhang3, and Jun Liu1
1The Second Xiangya Hospital, Central South University, Changsha, China, 2MR Applicationļ¼ŒSiemens Healthineers Ltd., Changsha, China, 3MR Scientific Marketingļ¼ŒSiemens Healthineers Ltd., Wuhan, China

Synopsis

Keywords: White Matter, Diffusion/other diffusion imaging techniquesThis study aimed to explore the changes of brain white matter changes in short-term methamphetamine (MA) abstinence and to investigate potential imaging markers. Compared with healthy controls (HC), fractional anisotropy (FA), axial diffusivty (AD) and mean diffusivity (MD) values in short-term abstinence group were all increased, but there was no significant difference in the radial diffusivty value. The changes of FA, AD and MD value may be a new biomarker which is helpful to explore the potential mechanism of neurotoxicity damage.

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Keywords