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Abstract #2859

Microstructral and Functional Changes of brain in Pontine Infarction: A Combined Arterial Spin Labeling and Diffusion Tensor Imaging Study

Peipei Chang1, Peng Sun2, and Yanwei Miao1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, BeiJing, China

Synopsis

Keywords: Stroke, Perfusion, Arterial Spin LabelingPontine infarction (PI) is very common in posterior circulation infarction, which can lead to behavioral dysfunctions, such as motor and cognition impairment. However, secondary changes in microstructure after PI in the whole brain remain unclear. This study aimed to explore the changes in cerebral blood flow (CBF) and fractional anisotropy (FA) in PI patients and to better understand the whole brain microstructure changes. We found PI could lead to extensive white matter tracts impairment in most of the whole brain regions and perfusion changes in some brain regions.

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