Abstract #2860

Voxel-mirrored homotopic connectivity is impaired in cortical stroke but compensatory in subcortical stroke: a resting-state fMRI study

Changjiang Zhao^1,2, Chengxin Yu^1,2, Bo Rao ³, Junlong Pan¹, Li Zhu¹, Jiangjin Chen¹, Long Chen¹, Xiong Xiong ¹, Can Zhang ¹, Yong Ye¹, Zheng Wang ¹, Xiaoling Yang ¹, Lisi Xie ¹, Xiance Zhao⁴, Chen Zhao⁵, and Shan Huang⁴

¹Yichang Central People's Hospital and The First College of Clinical Medical Science, China Three Gorges University, Yichang, China, ²Institute of Medcical Imaging, China Three Gorges University, Yichang, China, ³Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China, ⁴Philips Healthcare, Shanghai, China, ⁵Philips Healthcare, Guangzhou, China

Synopsis

Keywords: Stroke, fMRI (resting state)The alteration patterns of bi-hemispheric coordination between homologous areas in the whole brain of acute ischemic stroke patients with different infarct sites remains unclear. In the analysis of the voxel-mirrored homotopic connectivity (VMHC) among patients with frontoparietal lesion (G1), radiation coronal lesion (G2) and basal ganglia lesion (G3), VMHC was significantly decreased in G1 compared with G2 and G3. The impaired regions, such as precentral gyrus and postcentral gyrus, were part of the sensorimotor and default mode network. In contrast, VMHC mostly increased in patients with subcortical stroke, which indicates compensation rather than impairment of bi-hemispheric coordination.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.