Abstract #2862

Association of brain connections in anterior and posterior circulation with the side of asymptomatic internal carotid stenosis and verbal memory

Jyun-Ru Chen¹, Chun-Jen Lin^2,3, I-Hui Lee^2,3,4, and Chia-Feng Lu¹

¹Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan, ²School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ³Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ⁴Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan

Synopsis

Keywords: Vessels, IschemiaPrevious studies have reported that patients with asymptomatic internal carotid stenosis (aICS) had recall verbal memory impairment. However, the underlying mechanism to elucidate the altered functional connectivity (FC) associated with the anterior and posterior circulation was not proposed. Furthermore, whether the laterality of aICS is a factor in FC alterations and verbal memory impairment requires further investigation. In this study, we reported that the left and right aICS groups showed different patterns of FC changes related to secondary language regions in anterior and posterior circulation. These FCs could be served as imaging biomarkers for recall verbal memory.

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