Abstract #2886

Effects of SMS accelerating factor on stability of radiomics features from quantitative parametric maps of IVIM and DKI in Cervical Cancer

Ai Shuangquan^1,2, Peng Wei¹, He Yaoyao¹, Zhang Huiting³, Grimm Robert⁴, Zhang Zhaoxi¹, Peng Lin⁵, Liu Yulin¹, and Yuan Zilong¹

¹Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, ²School of Biomedical Engineering, South-Central Minzu University, Wuhan, China, ³MR Scientific Marketing, Siemens Healthcare, Wuhan, China, Wuhan, China, ⁴MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, Erlangen, Germany, ⁵Department of Gynecology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Synopsis

Keywords: Radiomics, Cancer, Cervical CancerThe aim of this study was to explore the effects of SMS on radiomics features in quantitative parametric maps based on IVIM and DKI models. Meanwhile, the effects of whole-tumor and maximal-tumor layer delineation on radiomics features were compared, whether stable features are associated with clinical staging of cervical cancer was analyzed. The results showed that SMS had the greatest effect on features extracted from D* and f map from IVIM model and the least effect on features extracted from ADC map; SMS had a greater effect on the radiomics features extracted by maximum-tumor layer delineation than by whole-tumor delineation.

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