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Abstract #2891

Radiomics-based Machine Learning for Predicting Clinically Significant Cancer in Multicenter Cohort: Comparison to PI-RADS Reading

Gabriel Addio Nketiah1,2, Mohammed RS Sunoqrot 1,3, Elise Sandsmark3, Sverre Langørgen 3, Kirsten M Selnæs 1,3, Helena Bertilsson 1,4, Mattijs Elschot 1,3, and Tone F Bathen1,3
1Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway, 2Department of Radiology and Nuclear Medicine, St. Olavs Hospital, Trondheim University Hospital,, Trondheim, Norway, 3Department of Radiology and Nuclear Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, 4Department of Urology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway

Synopsis

Keywords: Machine Learning/Artificial Intelligence, ProstateSynopsis: Recently, predictive machine learning models have shown promise for prostate cancer diagnosis. The utility of MRI radiomic features for prostate cancer detection and classification has been shown several studies, but mostly using relatively small and single centre cohort. In this study, we showed that radiomics-based machine learning can perform relatively well compared to clinical practice, especially in large multicentre settings. On the patient-level analysis, the areas under the receiver-operating curves for PI-RADS reading by a radiologist and machine learning model were 90% and 89%, respectively.

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