Abstract #2892

The Impact of Compressed Sensing on Radiomics of Fast Anatomical MRI of Rat Brain at 7T

Arda Arpak¹, Esra Sümer¹, Asım Samlı¹, Pınar S. Özbay¹, Uluç Pamuk^2,3, Kübra Çağlar², Elif M. Demir², Mehmet Yumak², Can A. Yucesoy¹, and Esin Ozturk-Isik¹

¹Institute of Biomedical Engineering, Boğaziçi University, İstanbul, Turkey, ²Targeted Therapy Technologies Experimental Animal Imaging Laboratory, Boğaziçi University, İstanbul, Turkey, ³Department of Biomedical Engineering, İstinye University, İstanbul, Turkey

Synopsis

Keywords: Image Reconstruction, Preclinical, RadiomicsThis study aims to investigate the effect of compressed sensing reconstruction on radiomics parameters of rat brain MRI at 7T. T2 weighted MRI of rat brain were randomly under-sampled with R=2.2 and reconstructed using compressed sensing. Brains were segmented after registration to a Wistar rat brain atlas. The radiomics of original and accelerated MRI data were compared in seven scans of rat brains using a Wilcoxon signed-rank test. Stable radiomics features were identified using intraclass correlation coefficients. The findings of this study indicated that not all radiomics features of rat brain were robust to compressed sensing acceleration.

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