Keywords: Data Analysis, BrainSubstance use disorder (SUD) affects the structure, function, and metabolism of the brain, and MR imaging helps to track and manage the therapeutic efficacy. We analyzed cortical white matter and Amygdala regions for 5 patients with cannabis use disorder using changes in texture and volume. Each patient was scanned 4 times(at 0,2,12 and 24 weeks) with 3D fast spin echo on a 3T scanner. We found increased textural changes across intervals for cortical white matter. However, for Amygdala, volumetric changes were greater in weeks 2 and 12.Both these changes help in the early monitoring of the effectiveness of the therapy.
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