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Abstract #2904

Increasing temporal SNR, sharpness, specificity, and sensitivity of ASLfMRI using the partial separability model

Charles John Marchini1 and Brad Sutton 1
1Bioengineering, University of Illinois Urbana-Champaign, Urbana, IL, United States

Synopsis

Keywords: Sparse & Low-Rank Models, Arterial spin labellingASLfMRI temporal SNR (tSNR) and sharpness in the inferior-superior direction was improved by using partial separability, a low rank model. The method requires an additional novelty to the partial separable model which allows time points with no corresponding imaging data, only temporal navigator data, to be reconstructed. A finger tapping task was used to demonstrate the detection of cerebral blood flow to the motor cortex. Mean squared error, structural similarity index, and the area under the curve of a receiver operating characteristic curve was also improved as shown by using a simulation of ASLfMRI data.

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Keywords