Abstract #2945

The effects of brain diffusion MRI preprocessing pipelines in a clinical study of neurodegenerative disease

Kouhei Kamiya^1,2, Sayori Hanashiro³, Osamu Kano³, Koji Kamagata², Masaaki Hori^1,2, and Shigeki Aoki²

¹Department of Radiology, Toho University, Faculty of Medicine, Tokyo, Japan, ²Department of Radiology, Juntendo University, Faculty of Medicine, Tokyo, Japan, ³Department of Neurology, Toho University, Faculty of Medicine, Tokyo, Japan

Synopsis

Keywords: Data Processing, Diffusion/other diffusion imaging techniques, Image preprocessingThe impacts of different diffusion MRI preprocessing pipelines on the statistical results of clinical studies were investigated in amyotrophic lateral sclerosis. The results illustrate the influences of popular preprocessing tools on the effect size of the disease in DKI metrics.

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