Abstract #2958

Predicting the Risk of Non-Saccular Aneurysms Based on the Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Yan Li¹, Ziming Xu¹, Linggen Dong², Yajie Wang¹, Peng Liu², Ming Lv², and Huijun Chen¹

¹Center for Biomedical Imaging Research, Tsinghua University, Beijing, China, ²Department of Neurosurgery, Beijing Tiantan Hospital, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China

Synopsis

Keywords: Data Analysis, DSC & DCE Perfusion

Assessment of intracranial aneurysm rupture risk is clinically critical. Recent studies have shown that the aneurysm wall permeability (K^trans) and wall enhancement index are independent risk factors for predicting saccular aneurysm rupture. However, this conclusion has not been confirmed in non-saccular aneurysms. Our study suggested that K^trans was significantly associated with the aneurysm size and PHASES score in non-saccular aneurysms. But K^trans did not associate with the wall enhancement index in non-saccular aneurysms. Therefore, K^trans can provide an independent quantitative indicator for assessing the risk of rupture of in non-saccular intracranialaneurysms.

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