Abstract #3017

Changes in brain pulsatility associated with heart rate elevation using amplified MRI and phase-contrast MRI

Haribalan Kumar^1,2,3, Haylea Rodgers^3,4, Jet Wright^3,4, Ben Bristow^3,4, Paul Condron^3,5, Taylor Emsden^3,5, Davidson Taylor^3,6, Samantha Holdsworth^3,5, Soroush Safaei², Gonzalo Maso Talou², Josh McGeown³, Ed Maunder⁷, and Eryn Kwon^2,3,5

¹GE Healthcare, Gisborne, New Zealand, ²Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, ³Mātai Medical Research Institute, Gisborne, New Zealand, ⁴University of Otago, Dunedin, New Zealand, ⁵Faculty of Medical and Health Sciences & Centre for Brain Research, University of Auckland, Auckland, New Zealand, ⁶Ngai Tāmanuhiri, Rongowhakaata, Ngāti Porou, Tūranganui-a-Kiwa, Tūranganui-a-Kiwa, Tairāwhiti, New Zealand, ⁷Sports Performance Research Institute New Zealand, Auckland University of Technology, Auckland, New Zealand

Synopsis

Keywords: Neurofluids, Neuroscience, Brain motion, image analysisCardiac pulsatility is a key driver of brain pulsatility. However, changes in brain pulsatility in response to changes in heart rate have been sparsely studied. Using a combination of amplified MRI and phase-contrast MRI, brain parenchyma motion, blood flow, and CSF flow were measured and assessed during rhythmic hand-grip exercise to help understand the role of heart rate on brain physiology. This approach opens opportunities for probing the role of heart rate, brain fluid, and motion flow in various pathologies that affect the brain.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.