Abstract #3059

Relative Cerebral Blood Volume Differences Between Adult-Type Diffuse Glioma Subgroups According to WHO 2021: A Study of 146 Gliomas

Buse Buz-Yalug¹, Ayca Ersen Danyeli^2,3, M. Cengiz Yakicier^3,4, M. Necmettin Pamir^3,5, Koray Ozduman^3,5, Alp Dincer^3,6, and Esin Ozturk-Isik^1,3

¹Institute of Biomedical Engineering, Bogazici University, Istanbul, Turkey, ²Department of Medical Pathology, Acibadem University, Istanbul, Turkey, ³Brain Tumor Research Group, Acibadem University, Istanbul, Turkey, ⁴Department of Molecular Biology and Genetics, Acibadem University, Istanbul, Turkey, ⁵Department of Neurosurgery, Acibadem University, Istanbul, Turkey, ⁶Department of Radiology, Acibadem University, Istanbul, Turkey

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Machine Learning/Artificial IntelligenceThe main purpose of this study is to analyze the relative cerebral blood volume (rCBV) differences of adult diffuse glioma subgroups defined in the updated WHO 2021 brain tumor classification. The IDH wildtype group had statistically significantly higher rCBV values, and IDH mutational subgroups were classified with 82.5% accuracy (precision = 82.1%, recall = 82.9%), while the accuracies of glioblastoma and oligodendroglioma classification was 81.9%, glioblastoma and astrocytoma classification was 83.3%, and astrocytoma and oligodendroglioma classification was 77.5%.

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