Meeting Banner
Abstract #3073

Evaluation of multi-echo-based Hybrid-EPI (HEPI) technique for measuring brain oxygenation

Krishnapriya Venugopal1, Esther A.H Warnert1, Daniëlle van Dorth2, Marion Smits1, Matthias J.P van Osch2, Dirk H.J Poot1, and Juan Antonio Hernandez-Tamames1,3
1Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands, 3Medical Imaging, TU Delft, Delft, Netherlands

Synopsis

Keywords: Data Acquisition, Brain, Oxygenation

The reversible component of transverse relaxation time, R2’, enables the measurement of blood oxygenation, an important biomarker in several diseases. We propose a multi-echo HEPI technique to estimate R2’. HEPI combines GRE and SE and hence provides R2* and R2, when acquired at different echo-times. The accuracy of ME-HEPI in measuring R2’ is evaluated in a phantom in this work. The sensitivity of HEPI to different oxygenation levels, attained using respiratory challenge MRI, is studied in a healthy subject. This is also investigated using a simulation tool that simulates microvasculature and MR signal for varying oxygenation in the vessels.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords