Abstract #3075

Early Prediction of Response to Neoadjuvant Systemic Therapy of Triple Negative Breast Cancer using Radiomics on DCE-MRI

Bikash Panthi¹, Sanaz Pashapoor¹, Beatriz E. Adrada¹, Rosalind P. Candelaria¹, Mary S. Guirguis¹, Miral M. Patel¹, Rania M. Mohamed¹, Medine Boge¹, Zijian Zhou¹, Jong Bum Son¹, Ken-Pin Hwang¹, Huong T.C. Le-Petross¹, Jessica W.T. Leung¹, Marion E. Scoggins¹, Gary J. Whitman¹, Zhan Xu¹, Deanna L. Lane¹, Tanya Moseley¹, Frances Perez¹, Jason White¹, Elizabeth Ravenberg¹, Alyson Clayborn¹, Huiqin Chen¹, Jia Sun¹, Peng Wei¹, Alastair Thompson², Stacy Moulder¹, Anil Korkut¹, Lei Huo¹, Kelly K. Hunt¹, Jennifer K. Litton¹, Vicente Valero¹, Debu Tripathy¹, Wei Yang¹, Clinton Yam¹, Gaiane M Rauch¹, and Jingfei Ma¹

¹MD Anderson Cancer Center, Houston, TX, United States, ²Baylor College of Medicine, Houston, TX, United States

Synopsis

Keywords: Radiomics, fMRI, Treatment responseWe developed models based on radiomic features from dynamic contrast enhanced (DCE) MR images and demonstrated that these models have potential to serve as non-invasive biomarkers for early prediction of pathologic complete response (pCR) in triple negative breast cancer (TNBC) patients undergoing neoadjuvant systemic therapy (NAST).

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.