Abstract #3087

Super-resolution reconstruction of time-resolved four-dimensional computed tomography (TR-4DCT) with multiple breaths based on TR-4DMRI

Yilin Liu¹, Asala Ahamd¹, Xingyu Nie², and Guang (George) Li¹

¹Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, ²Radiology, University of Kentucky, Lexington, KY, United States

Synopsis

Keywords: Image Reconstruction, Radiotherapy, time-resolved 4DMRI, time-resolved 4DCT, multi-breathing cyclesThis study has demonstrated that the feasibility to reconstruct multiple-breath TR-4DCT via the super-resolution reconstruction framework through either CT^4D→(MR^BH→MR^FB) or (CT^4D←MR^BH)→ MR^FB deformable image registration. Using TR-4DCT, potential dosimetry consequences in radiotherapy of lung, liver, and pancreatic patients due to patient breathing irregularities can be readily assessed.

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