Meeting Banner
Abstract #3094

Implementation of Hyperpolarized 129Xe Accelerated MRI in Phantom and Human Lungs: Preliminary Study and Troubleshooting

Samuel Perron1, Matthew S. Fox1,2, and Alexei V. Ouriadov1,2,3
1Physics and Astronomy, University of Western Ontario, London, ON, Canada, 2Lawson Health Research Institute, London, ON, Canada, 3School of Biomedical Engineering, University of Western Ontario, London, ON, Canada

Synopsis

Keywords: Data Acquisition, Low-Field MRIAccelerated MRI could significantly improve image quality of lung imaging without increasing costs, especially for low field strengths. The signal decay of a series of undersampled xenon-129 images is fitted to the Stretched-Exponential-Model to yield higher SNR. The proposed method was implemented in undersampled phantom images at low field (0.074T) and human lung images at high field (3T) using the FGRE pulse sequence with hyperpolarized 129Xe; SNR was significantly improved within the same scan duration compared to a fully-sampled image. Potential issues with the compressed-sensing reconstruction are identified and possible solutions presented to promote robustness of method.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords