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Abstract #3104

Task-based evaluation of deep learning-based reconstruction for highly-accelerated 3D T1-weighted brain MRI scans

Sangtae Ahn1, Chitresh Bhushan1, John Huston2, J. Kevin DeMarco3, Robert Y. Shih3,4, Joshua D. Trzasko2, Rafi Brada5, Graeme Mckinnon6, Isabelle Heukensfeldt Jansen1, Dan Rettmann7, Brian Burns8, Ty A. Cashen6, Nir Mazor5, Xucheng Zhu8, and Thomas K. Foo1
1GE Research, Niskayuna, NY, United States, 2Mayo Clinic College of Medicine, Rochester, MN, United States, 3Walter Reed National Military Medical Center, Bethesda, MD, United States, 4Uniformed Services University of the Health Sciences, Bethesda, MD, United States, 5GE Research, Herzliya, Israel, 6GE HealthCare, Waukesha, WI, United States, 7GE HealthCare, Rochester, MN, United States, 8GE HealthCare, Menlo Park, CA, United States

Synopsis

Keywords: Image Reconstruction, Machine Learning/Artificial Intelligence, Brain, Neuro3D MRI enables thin slices at the cost of long scan times, causing practical challenges. Recently, deep-learning (DL) techniques have successfully accelerated MR scans. However, it is challenging to characterize the image quality (IQ) performance of DL methods by conventional metrics because IQ depends on applications, i.e., how images are used. We evaluate the IQ performance of DL-Speed, our DL-based acceleration method, for 3D T1-weighted MPRAGE brain scans, in 1) post-reconstruction subcortical structure segmentation, and 2) a reader study. The results imply DL-Speed can accelerate scans with reduction factor R=10 while maintaining IQ comparable to standard parallel imaging with R=2.1.

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Keywords