Keywords: Liver, ElastographyMR elastography (MRE) derived liver stiffness measurements (LSMs) require manual drawing of ROIs on elastogram images. These ROIs may differ in size, and some clinicians suggest that reporting mean stiffness weighted by ROI area is more accurate than the unweighted mean. In this study the unweighted and weighted mean liver stiffness were calculated for 161 patients undergoing liver MRE exams using various scanning hardware/field strengths, and the statistical significance of the difference between the two sets of LSMs was tested using a paired two-tailed t-test. No statistically significant differences were found between weighted and unweighted LSMs.
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