Abstract #3150

Building a Liver Perfusion Phantom for Vessel Size Imaging

Dominick Jon Romano¹, Mert Şişman^2,3, Qihao Zhang^1,3, Thanh Nguyen³, Pascal Spincemaille³, Martin Prince^3,4, and Yi Wang^1,3

¹Biomedical Engineering, Cornell University, Ithaca, NY, United States, ²Electrical & Computer Engineering, Cornell University, Ithaca, NY, United States, ³Radiology, Weill Cornell Medical College, New York, NY, United States, ⁴Radiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States

Synopsis

Keywords: Liver, VesselsWe have developed a methodology of preparing explant livers for perfusion and vessel size imaging. Off-label use of ferumoxytol is known to provide high quality vessel size maps in vivo; however, known adverse reactions to ferumoxytol may hinder adoption into the clinical workflow. In this case, gadolinium may be more attractive. VSI experiments on a gadolinium perfused liver provide a proof of concept that Gadolinium may be used as an alternative contrast for vessel size imaging.

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