Keywords: CEST & MT, CEST & MTIt is well-known that the refocusing flip angles (FAs) of the SPACE sequence can be optimized to generate different image contrasts, such as T1-weighted or T2-weighted. However, the existing SPACE variable FA scheme is unsuitable for CEST imaging whose utmost aim is to increase the SNR during signal readout instead of enforcing contrast. Here, we derived a model to describe the signal-to-noise ratio (SNR) of the SPACE sequence, and maximized SNR by varying refocusing flip angles. Compared to the original constant FA protocol, the optimized variable flip angles yielded both SNR and resolution improvement.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords